1. |
ZMPSTE24 |
ENSGALG00000000855 |
5144 |
10 |
1.000 |
1.000 |
1.000 |
1.000 |
1.000 |
1.000 |
1.000 |
1.000 |
1.000 |
1.000 |
zinc metallopeptidase STE24 [Source:HGNC Symbol;Acc:HGNC:12877] |
2. |
MRPS30 |
ENSGALG00000014874 |
3416 |
1.58 |
- |
- |
- |
- |
- |
- |
0.807 |
0.773 |
- |
- |
mitochondrial ribosomal protein S30 [Source:NCBI gene;Acc:395781] |
3. |
SF3B3 |
ENSGALG00000002531 |
19397 |
1.579 |
- |
- |
- |
- |
- |
- |
0.804 |
0.775 |
- |
- |
splicing factor 3b subunit 3, transcript variant X2 |
4. |
AGFG1 |
ENSGALG00000003052 |
4766 |
1.565 |
- |
- |
0.792 |
- |
- |
- |
0.773 |
- |
- |
- |
ArfGAP with FG repeats 1 [Source:HGNC Symbol;Acc:HGNC:5175] |
5. |
PEMT |
ENSGALG00000004875 |
4094 |
1.536 |
- |
- |
0.778 |
- |
- |
- |
- |
0.758 |
- |
- |
phosphatidylethanolamine N-methyltransferase [Source:NCBI gene;Acc:416508] |
6. |
PPFIA1 |
ENSGALG00000035774 |
5258 |
1.516 |
- |
- |
- |
- |
- |
- |
0.767 |
0.749 |
- |
- |
PTPRF interacting protein alpha 1 [Source:HGNC Symbol;Acc:HGNC:9245] |
7. |
ASH2L |
ENSGALG00000003233 |
4814 |
1.506 |
- |
- |
0.789 |
- |
- |
- |
- |
0.717 |
- |
- |
ASH2 like, histone lysine methyltransferase complex subunit [Source:NCBI gene;Acc:426774] |
8. |
LPCAT3 |
ENSGALG00000014570 |
7919 |
1.499 |
- |
- |
0.776 |
- |
- |
- |
- |
0.723 |
- |
- |
lysophosphatidylcholine acyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:30244] |
9. |
PAPSS1 |
ENSGALG00000010542 |
5631 |
1.49 |
- |
- |
- |
- |
- |
- |
0.740 |
0.750 |
- |
- |
3'-phosphoadenosine 5'-phosphosulfate synthase 1 [Source:HGNC Symbol;Acc:HGNC:8603] |
10. |
VTA1 |
ENSGALG00000013810 |
4998 |
1.489 |
- |
- |
0.738 |
- |
- |
- |
- |
0.751 |
- |
- |
vesicle trafficking 1 [Source:HGNC Symbol;Acc:HGNC:20954] |
11. |
ATR |
ENSGALG00000002663 |
4626 |
1.488 |
- |
- |
- |
- |
- |
- |
0.773 |
0.715 |
- |
- |
ATR serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:882] |
12. |
HINT3 |
ENSGALG00000044342 |
5674 |
1.485 |
- |
- |
0.726 |
- |
- |
- |
- |
0.759 |
- |
- |
histidine triad nucleotide binding protein 3 [Source:HGNC Symbol;Acc:HGNC:18468] |
13. |
ACTR8 |
ENSGALG00000005385 |
3647 |
1.478 |
- |
- |
- |
- |
- |
- |
0.741 |
0.737 |
- |
- |
ARP8 actin related protein 8 homolog [Source:HGNC Symbol;Acc:HGNC:14672] |
14. |
DDX10 |
ENSGALG00000017156 |
5657 |
1.47 |
- |
- |
- |
- |
- |
- |
0.747 |
0.723 |
- |
- |
DEAD-box helicase 10 [Source:NCBI gene;Acc:418965] |
15. |
FAM177A1 |
ENSGALG00000010046 |
4318 |
1.446 |
- |
- |
- |
- |
- |
- |
0.733 |
0.713 |
- |
- |
family with sequence similarity 177 member A1 [Source:NCBI gene;Acc:423323] |
16. |
NUPL1 |
NUPL1 |
8197 |
1.444 |
- |
- |
0.701 |
- |
- |
- |
0.743 |
- |
- |
- |
|
17. |
FAM133B |
|
9239 |
1.427 |
- |
- |
- |
- |
- |
- |
0.702 |
0.725 |
- |
- |
family with sequence similarity 133 member B |
18. |
NDOR1 |
ENSGALG00000008920 |
2342 |
1.42 |
- |
- |
0.719 |
- |
- |
- |
0.701 |
- |
- |
- |
NADPH dependent diflavin oxidoreductase 1 [Source:HGNC Symbol;Acc:HGNC:29838] |
19. |
SNX7 |
ENSGALG00000005478 |
4736 |
1.409 |
- |
- |
- |
- |
- |
- |
0.707 |
0.702 |
- |
- |
sorting nexin 7 [Source:HGNC Symbol;Acc:HGNC:14971] |
20. |
GSKIP |
ENSGALG00000011088 |
3421 |
0.869 |
- |
- |
- |
- |
- |
- |
- |
0.869 |
- |
- |
GSK3B interacting protein [Source:NCBI gene;Acc:423442] |
21. |
MORN4 |
ENSGALG00000006149 |
7772 |
0.839 |
- |
- |
- |
- |
- |
- |
- |
0.839 |
- |
- |
MORN repeat containing 4 [Source:NCBI gene;Acc:425290] |
22. |
ATP6AP1 |
ENSGALG00000008836 |
4343 |
0.825 |
- |
- |
- |
- |
- |
- |
- |
0.825 |
- |
- |
ATPase H+ transporting accessory protein 1 [Source:NCBI gene;Acc:427854] |
23. |
CDR2L |
ENSGALG00000026295 |
4142 |
0.823 |
- |
- |
- |
- |
- |
- |
- |
0.823 |
- |
- |
cerebellar degeneration related protein 2 like [Source:HGNC Symbol;Acc:HGNC:29999] |
24. |
ADI1 |
ENSGALG00000025796 |
8636 |
0.821 |
- |
- |
- |
- |
- |
- |
- |
0.821 |
- |
- |
acireductone dioxygenase 1 [Source:NCBI gene;Acc:421918] |
25. |
UBFD1 |
ENSGALG00000006117 |
5242 |
0.821 |
- |
- |
- |
- |
- |
- |
- |
0.821 |
- |
- |
ubiquitin family domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30565] |
26. |
MED7 |
ENSGALG00000003870 |
4244 |
0.819 |
- |
- |
- |
- |
- |
- |
- |
0.819 |
- |
- |
mediator complex subunit 7 [Source:HGNC Symbol;Acc:HGNC:2378] |
27. |
ZNF622 |
ENSGALG00000037171 |
5706 |
0.818 |
- |
- |
- |
- |
- |
- |
- |
0.818 |
- |
- |
zinc finger protein 622 [Source:NCBI gene;Acc:373921] |
28. |
SQSTM1 |
ENSGALG00000035804 |
2238 |
0.816 |
- |
- |
- |
- |
- |
- |
- |
0.816 |
- |
- |
sequestosome 1 [Source:HGNC Symbol;Acc:HGNC:11280] |
29. |
TM4SF18 |
|
4553 |
0.812 |
- |
- |
- |
- |
- |
- |
0.812 |
- |
- |
- |
transmembrane 4 L six family member 18, transcript variant X2 |
30. |
TFDP2 |
ENSGALG00000025759 |
13407 |
0.811 |
- |
- |
- |
- |
- |
- |
- |
0.811 |
- |
- |
transcription factor Dp-2 [Source:NCBI gene;Acc:424780] |
31. |
NDUFS5 |
ENSGALG00000003625 |
27698 |
0.811 |
- |
- |
- |
- |
- |
- |
- |
0.811 |
- |
- |
NADH:ubiquinone oxidoreductase subunit S5 [Source:HGNC Symbol;Acc:HGNC:7712] |
32. |
PRKACB |
ENSGALG00000028530 |
12506 |
0.809 |
- |
- |
- |
- |
- |
- |
- |
0.809 |
- |
- |
protein kinase cAMP-activated catalytic subunit beta, transcript variant X2 |
33. |
TIMM13 |
ENSGALG00000028937 |
32013 |
0.808 |
- |
- |
- |
- |
- |
- |
- |
0.808 |
- |
- |
translocase of inner mitochondrial membrane 13 [Source:NCBI gene;Acc:100859352] |
34. |
MYEOV2 |
MYEOV2 |
5155 |
0.807 |
- |
- |
- |
- |
- |
- |
- |
0.807 |
- |
- |
|
35. |
PEF1 |
ENSGALG00000040519 |
8522 |
0.806 |
- |
- |
- |
- |
- |
- |
0.806 |
- |
- |
- |
penta-EF-hand domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30009] |
36. |
ENSGALG00000005615 |
ENSGALG00000005615 |
4354 |
0.804 |
- |
- |
- |
- |
- |
- |
0.804 |
- |
- |
- |
|
37. |
TAF2 |
ENSGALG00000043193 |
6311 |
0.802 |
- |
- |
- |
- |
- |
- |
- |
0.802 |
- |
- |
TATA-box binding protein associated factor 2 [Source:NCBI gene;Acc:428389] |
38. |
WDR3 |
ENSGALG00000014791 |
5856 |
0.801 |
- |
- |
0.801 |
- |
- |
- |
- |
- |
- |
- |
WD repeat domain 3 [Source:NCBI gene;Acc:427952] |
39. |
TRAPPC4 |
ENSGALG00000007707 |
3568 |
0.801 |
- |
- |
- |
- |
- |
- |
- |
0.801 |
- |
- |
trafficking protein particle complex 4 [Source:NCBI gene;Acc:419788] |
40. |
PDDC1 |
|
5179 |
0.798 |
- |
- |
- |
- |
- |
- |
0.798 |
- |
- |
- |
Parkinson disease 7 domain containing 1, transcript variant X6 |
41. |
ILF2 |
ENSGALG00000011570 |
23050 |
0.798 |
- |
- |
- |
- |
- |
- |
0.798 |
- |
- |
- |
interleukin enhancer binding factor 2 [Source:HGNC Symbol;Acc:HGNC:6037] |
42. |
TMEM14A |
ENSGALG00000019894 |
5279 |
0.798 |
- |
- |
- |
- |
- |
- |
- |
0.798 |
- |
- |
transmembrane protein 14A [Source:HGNC Symbol;Acc:HGNC:21076] |
43. |
ATL2 |
ENSGALG00000037289 |
7926 |
0.794 |
- |
- |
- |
- |
- |
- |
- |
0.794 |
- |
- |
atlastin GTPase 2 [Source:HGNC Symbol;Acc:HGNC:24047] |
44. |
ATP6V1E1 |
ENSGALG00000013036 |
13497 |
0.792 |
- |
- |
0.792 |
- |
- |
- |
- |
- |
- |
- |
ATPase H+ transporting V1 subunit E1 [Source:NCBI gene;Acc:418162] |
45. |
TPRKB |
ENSGALG00000013018 |
8687 |
0.791 |
- |
- |
- |
- |
- |
- |
0.791 |
- |
- |
- |
TP53RK binding protein [Source:HGNC Symbol;Acc:HGNC:24259] |
46. |
RPAP3 |
ENSGALG00000009743 |
3380 |
0.79 |
- |
- |
- |
- |
- |
- |
- |
0.790 |
- |
- |
RNA polymerase II associated protein 3 [Source:NCBI gene;Acc:417811] |
47. |
STT3A |
ENSGALG00000042730 |
7834 |
0.789 |
- |
- |
- |
- |
- |
- |
0.789 |
- |
- |
- |
Gallus gallus STT3A, catalytic subunit of the oligosaccharyltransferase complex (STT3A), mRNA. [Source:RefSeq mRNA;Acc:NM_001318991] |
48. |
IFT57 |
ENSGALG00000015356 |
5540 |
0.787 |
- |
- |
0.787 |
- |
- |
- |
- |
- |
- |
- |
intraflagellar transport 57 [Source:HGNC Symbol;Acc:HGNC:17367] |
49. |
DHX30 |
ENSGALG00000039830 |
5187 |
0.785 |
- |
- |
- |
- |
- |
- |
0.785 |
- |
- |
- |
DExH-box helicase 30 [Source:NCBI gene;Acc:420376] |
50. |
DAD1 |
ENSGALG00000035626 |
32604 |
0.784 |
- |
- |
- |
- |
- |
- |
- |
0.784 |
- |
- |
defender against cell death 1 [Source:NCBI gene;Acc:395343] |
51. |
NUP214 |
ENSGALG00000041111 |
4902 |
0.783 |
- |
- |
- |
- |
- |
- |
- |
0.783 |
- |
- |
nucleoporin 214 [Source:HGNC Symbol;Acc:HGNC:8064] |
52. |
NUP85 |
ENSGALG00000007974 |
21249 |
0.783 |
- |
- |
- |
- |
- |
- |
- |
0.783 |
- |
- |
nucleoporin 85 [Source:NCBI gene;Acc:422120] |
53. |
DACH1 |
ENSGALG00000037015 |
5648 |
0.782 |
- |
- |
0.782 |
- |
- |
- |
- |
- |
- |
- |
dachshund family transcription factor 1 [Source:NCBI gene;Acc:373935] |
54. |
IFT74 |
ENSGALG00000001801 |
1932 |
0.781 |
- |
- |
- |
- |
- |
- |
- |
0.781 |
- |
- |
intraflagellar transport 74 [Source:HGNC Symbol;Acc:HGNC:21424] |
55. |
EXOC2 |
ENSGALG00000012837 |
4914 |
0.781 |
- |
- |
- |
- |
- |
- |
- |
0.781 |
- |
- |
exocyst complex component 2 [Source:NCBI gene;Acc:420889] |
56. |
UPF2 |
ENSGALG00000033772 |
9548 |
0.78 |
- |
- |
- |
- |
- |
- |
0.780 |
- |
- |
- |
UPF2, regulator of nonsense mediated mRNA decay [Source:HGNC Symbol;Acc:HGNC:17854] |
57. |
BLMH |
ENSGALG00000004259 |
36907 |
0.779 |
- |
- |
- |
- |
- |
- |
- |
0.779 |
- |
- |
bleomycin hydrolase [Source:NCBI gene;Acc:395996] |
58. |
CSRP2BP |
CSRP2BP |
4679 |
0.779 |
- |
- |
- |
- |
- |
- |
- |
0.779 |
- |
- |
|
59. |
PPP1R2 |
ENSGALG00000029789 |
11594 |
0.779 |
- |
- |
- |
- |
- |
- |
0.779 |
- |
- |
- |
protein phosphatase 1 regulatory inhibitor subunit 2 [Source:NCBI gene;Acc:424894] |
60. |
AMBRA1 |
ENSGALG00000008358 |
2865 |
0.779 |
- |
- |
0.779 |
- |
- |
- |
- |
- |
- |
- |
autophagy and beclin 1 regulator 1 [Source:HGNC Symbol;Acc:HGNC:25990] |
61. |
CHN1 |
ENSGALG00000009293 |
6415 |
0.778 |
- |
- |
- |
- |
- |
- |
0.778 |
- |
- |
- |
chimerin 1 [Source:NCBI gene;Acc:429021] |
62. |
RNPS1 |
ENSGALG00000009288 |
13588 |
0.776 |
- |
- |
- |
- |
- |
- |
0.776 |
- |
- |
- |
RNA binding protein with serine rich domain 1 [Source:HGNC Symbol;Acc:HGNC:10080] |
63. |
BRMS1L |
ENSGALG00000010093 |
4964 |
0.775 |
- |
- |
- |
- |
- |
- |
0.775 |
- |
- |
- |
BRMS1 like transcriptional repressor [Source:NCBI gene;Acc:423328] |
64. |
MRPS23 |
ENSGALG00000005559 |
10360 |
0.774 |
- |
- |
0.774 |
- |
- |
- |
- |
- |
- |
- |
mitochondrial ribosomal protein S23 [Source:HGNC Symbol;Acc:HGNC:14509] |
65. |
PRKRIP1 |
ENSGALG00000001833 |
5092 |
0.773 |
- |
- |
- |
- |
- |
- |
0.773 |
- |
- |
- |
PRKR interacting protein 1 [Source:NCBI gene;Acc:417508] |
66. |
ATP5A1 |
ATP5A1 |
32367 |
0.773 |
- |
- |
- |
- |
- |
- |
- |
0.773 |
- |
- |
|
67. |
MRPL41 |
ENSGALG00000008746 |
3833 |
0.772 |
- |
- |
- |
- |
- |
- |
- |
0.772 |
- |
- |
mitochondrial ribosomal protein L41 [Source:NCBI gene;Acc:417261] |
68. |
IFNGR2 |
ENSGALG00000032660 |
2634 |
0.772 |
- |
- |
- |
- |
- |
- |
- |
0.772 |
- |
- |
interferon gamma receptor 2 [Source:NCBI gene;Acc:418502] |
69. |
SLC38A2 |
ENSGALG00000008497 |
3894 |
0.772 |
- |
- |
- |
- |
- |
- |
- |
0.772 |
- |
- |
solute carrier family 38 member 2 [Source:NCBI gene;Acc:417807] |
70. |
ENSGALG00000004711 |
ENSGALG00000004711 |
7347 |
0.772 |
- |
- |
- |
- |
- |
- |
- |
0.772 |
- |
- |
|
71. |
C1orf174 |
ENSGALG00000000975 |
4947 |
0.772 |
- |
- |
- |
- |
- |
- |
0.772 |
- |
- |
- |
chromosome 1 open reading frame 174 [Source:HGNC Symbol;Acc:HGNC:27915] |
72. |
C11H16ORF80 |
C11H16ORF80 |
18673 |
0.771 |
- |
- |
- |
- |
- |
- |
- |
0.771 |
- |
- |
|
73. |
AXIN2 |
ENSGALG00000039200 |
2333 |
0.771 |
- |
- |
- |
- |
- |
- |
0.771 |
- |
- |
- |
axin 2 [Source:NCBI gene;Acc:395152] |
74. |
TLE1 |
ENSGALG00000012575 |
2047 |
0.771 |
- |
- |
0.771 |
- |
- |
- |
- |
- |
- |
- |
transducin like enhancer of split 1 [Source:HGNC Symbol;Acc:HGNC:11837] |
75. |
FADS1 |
ENSGALG00000007127 |
5231 |
0.77 |
- |
- |
- |
- |
- |
- |
- |
0.770 |
- |
- |
fatty acid desaturase 1 |
76. |
SRSF5 |
ENSGALG00000009421 |
8502 |
0.769 |
- |
- |
- |
- |
- |
- |
- |
0.769 |
- |
- |
serine and arginine rich splicing factor 5 [Source:NCBI gene;Acc:423258] |
77. |
NSUN2 |
ENSGALG00000013064 |
2005 |
0.769 |
- |
- |
- |
- |
- |
- |
- |
0.769 |
- |
- |
NOP2/Sun RNA methyltransferase family member 2 [Source:NCBI gene;Acc:420938] |
78. |
CASP6 |
ENSGALG00000012186 |
6639 |
0.768 |
- |
- |
- |
- |
- |
- |
- |
0.768 |
- |
- |
caspase 6 [Source:NCBI gene;Acc:395477] |
79. |
NEK6 |
ENSGALG00000001118 |
20333 |
0.768 |
- |
- |
- |
- |
- |
- |
0.768 |
- |
- |
- |
NIMA related kinase 6 [Source:NCBI gene;Acc:417101] |
80. |
ENSGALG00000028938 |
ENSGALG00000028938 |
18616 |
0.768 |
- |
- |
- |
- |
- |
- |
- |
0.768 |
- |
- |
|
81. |
TRAPPC6B |
ENSGALG00000010157 |
7567 |
0.767 |
- |
- |
- |
- |
- |
- |
- |
0.767 |
- |
- |
trafficking protein particle complex 6B [Source:NCBI gene;Acc:423337] |
82. |
INTS6L |
ENSGALG00000006157 |
2303 |
0.767 |
- |
- |
- |
- |
- |
- |
- |
0.767 |
- |
- |
integrator complex subunit 6 like, transcript variant X6 |
83. |
ATG3 |
ENSGALG00000015204 |
11277 |
0.766 |
- |
- |
- |
- |
- |
- |
0.766 |
- |
- |
- |
autophagy related 3 [Source:NCBI gene;Acc:418369] |
84. |
DPYSL2 |
ENSGALG00000000227 |
9668 |
0.766 |
- |
- |
- |
- |
- |
- |
0.766 |
- |
- |
- |
dihydropyrimidinase like 2 [Source:NCBI gene;Acc:395155] |
85. |
CDC45 |
ENSGALG00000001616 |
8432 |
0.766 |
- |
- |
- |
- |
- |
- |
0.766 |
- |
- |
- |
cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] |
86. |
CDC23 |
ENSGALG00000007610 |
11945 |
0.765 |
- |
- |
- |
- |
- |
- |
0.765 |
- |
- |
- |
cell division cycle 23 [Source:HGNC Symbol;Acc:HGNC:1724] |
87. |
RIOK2 |
ENSGALG00000015288 |
6280 |
0.765 |
- |
- |
- |
- |
- |
- |
- |
0.765 |
- |
- |
RIO kinase 2 [Source:NCBI gene;Acc:427278] |
88. |
SMPD3 |
ENSGALG00000034950 |
4335 |
0.764 |
- |
- |
0.764 |
- |
- |
- |
- |
- |
- |
- |
sphingomyelin phosphodiesterase 3 [Source:HGNC Symbol;Acc:HGNC:14240] |
89. |
PSMC3 |
ENSGALG00000008108 |
22922 |
0.763 |
- |
- |
- |
- |
- |
- |
0.763 |
- |
- |
- |
proteasome 26S subunit, ATPase 3 [Source:NCBI gene;Acc:423182] |
90. |
DDX42 |
ENSGALG00000000581 |
8780 |
0.763 |
- |
- |
- |
- |
- |
- |
- |
0.763 |
- |
- |
DEAD-box helicase 42 [Source:NCBI gene;Acc:419959] |
91. |
PCYOX1 |
ENSGALG00000013878 |
2200 |
0.762 |
- |
- |
0.762 |
- |
- |
- |
- |
- |
- |
- |
prenylcysteine oxidase 1 [Source:HGNC Symbol;Acc:HGNC:20588] |
92. |
GSK3B |
ENSGALG00000014977 |
7950 |
0.762 |
- |
- |
- |
- |
- |
- |
- |
0.762 |
- |
- |
glycogen synthase kinase 3 beta [Source:HGNC Symbol;Acc:HGNC:4617] |
93. |
NUDCD2 |
ENSGALG00000001726 |
6303 |
0.761 |
- |
- |
0.761 |
- |
- |
- |
- |
- |
- |
- |
NudC domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30535] |
94. |
MFAP1 |
ENSGALG00000028295 |
6043 |
0.761 |
- |
- |
- |
- |
- |
- |
- |
0.761 |
- |
- |
microfibrillar associated protein 1 [Source:NCBI gene;Acc:415586] |
95. |
SEC62 |
ENSGALG00000009379 |
15745 |
0.761 |
- |
- |
- |
- |
- |
- |
- |
0.761 |
- |
- |
SEC62 homolog, preprotein translocation factor [Source:NCBI gene;Acc:424993] |
96. |
NT5C3B |
ENSGALG00000003651 |
5190 |
0.76 |
- |
- |
0.760 |
- |
- |
- |
- |
- |
- |
- |
5'-nucleotidase, cytosolic IIIB [Source:NCBI gene;Acc:420034] |
97. |
STX16 |
ENSGALG00000007541 |
6458 |
0.76 |
- |
- |
- |
- |
- |
- |
0.760 |
- |
- |
- |
syntaxin 16 [Source:NCBI gene;Acc:419315] |
98. |
CTCF |
|
10811 |
0.759 |
- |
- |
- |
- |
- |
- |
0.759 |
- |
- |
- |
CCCTC-binding factor, transcript variant X2 |
99. |
ERLIN2 |
ENSGALG00000003092 |
18251 |
0.758 |
- |
- |
- |
- |
- |
- |
- |
0.758 |
- |
- |
ER lipid raft associated 2 [Source:HGNC Symbol;Acc:HGNC:1356] |
100. |
PCF11 |
ENSGALG00000017249 |
4714 |
0.758 |
- |
- |
- |
- |
- |
- |
- |
0.758 |
- |
- |
PCF11 cleavage and polyadenylation factor subunit, transcript variant X4 |