1. |
PPA1 |
ENSGALG00000004442 |
33355 |
10 |
1.000 |
1.000 |
1.000 |
1.000 |
1.000 |
1.000 |
1.000 |
1.000 |
1.000 |
1.000 |
pyrophosphatase (inorganic) 1 [Source:HGNC Symbol;Acc:HGNC:9226] |
2. |
TCF7L2 |
ENSGALG00000008883 |
13688 |
1.682 |
- |
- |
- |
- |
- |
- |
0.809 |
0.873 |
- |
- |
transcription factor 7-like 2 (T-cell specific, HMG-box) [Source:NCBI gene;Acc:395508] |
3. |
PPP4R2 |
ENSGALG00000007810 |
15127 |
1.682 |
- |
- |
- |
- |
- |
- |
0.832 |
0.850 |
- |
- |
protein phosphatase 4 regulatory subunit 2 [Source:NCBI gene;Acc:416098] |
4. |
MAEA |
ENSGALG00000013310 |
13230 |
1.643 |
- |
- |
- |
- |
0.917 |
- |
0.726 |
- |
- |
- |
macrophage erythroblast attacher [Source:NCBI gene;Acc:426024] |
5. |
BOD1L1 |
ENSGALG00000026470 |
9250 |
1.642 |
- |
- |
- |
- |
- |
- |
0.778 |
0.864 |
- |
- |
biorientation of chromosomes in cell division 1 like 1 [Source:HGNC Symbol;Acc:HGNC:31792] |
6. |
ZFX |
ENSGALG00000016327 |
5470 |
1.631 |
- |
- |
- |
- |
- |
- |
0.756 |
0.875 |
- |
- |
zinc finger protein, X-linked, transcript variant X4 |
7. |
ETFDH |
ENSGALG00000009442 |
7671 |
1.602 |
- |
- |
- |
- |
- |
- |
0.817 |
0.785 |
- |
- |
electron transfer flavoprotein dehydrogenase [Source:NCBI gene;Acc:428724] |
8. |
ALG6 |
ENSGALG00000010991 |
3258 |
1.595 |
- |
- |
- |
- |
- |
- |
0.734 |
0.861 |
- |
- |
ALG6, alpha-1,3-glucosyltransferase [Source:NCBI gene;Acc:395078] |
9. |
EIF4E2 |
ENSGALG00000007919 |
8163 |
1.594 |
- |
- |
- |
- |
- |
0.730 |
- |
0.864 |
- |
- |
eukaryotic translation initiation factor 4E family member 2 [Source:HGNC Symbol;Acc:HGNC:3293] |
10. |
CDC42SE2 |
ENSGALG00000027258 |
4725 |
1.578 |
- |
- |
- |
- |
0.715 |
- |
- |
0.863 |
- |
- |
CDC42 small effector 2 [Source:NCBI gene;Acc:768825] |
11. |
FH |
ENSGALG00000013165 |
13669 |
1.54 |
- |
- |
- |
- |
0.729 |
- |
0.811 |
- |
- |
- |
fumarate hydratase [Source:NCBI gene;Acc:420969] |
12. |
MKI67 |
ENSGALG00000025996 |
28136 |
1.526 |
- |
- |
- |
- |
0.733 |
- |
0.793 |
- |
- |
- |
marker of proliferation Ki-67, transcript variant X3 |
13. |
ARL5B |
ENSGALG00000008557 |
12887 |
1.526 |
- |
- |
- |
- |
- |
- |
0.808 |
0.718 |
- |
- |
ADP ribosylation factor like GTPase 5B [Source:NCBI gene;Acc:420513] |
14. |
PCBP4 |
ENSGALG00000027695 |
7937 |
1.49 |
- |
- |
- |
- |
0.703 |
- |
0.787 |
- |
- |
- |
poly(rC) binding protein 4 [Source:HGNC Symbol;Acc:HGNC:8652] |
15. |
ARHGDIB |
ENSGALG00000011738 |
39492 |
1.476 |
- |
- |
- |
- |
0.724 |
- |
0.752 |
- |
- |
- |
Rho GDP dissociation inhibitor beta [Source:NCBI gene;Acc:417941] |
16. |
NFASC |
ENSGALG00000031776 |
4264 |
1.446 |
- |
- |
- |
- |
0.724 |
- |
0.722 |
- |
- |
- |
neurofascin [Source:NCBI gene;Acc:419824] |
17. |
PTPN12 |
|
9302 |
1.416 |
- |
- |
- |
- |
0.707 |
- |
0.709 |
- |
- |
- |
protein tyrosine phosphatase, non-receptor type 12 |
18. |
EIF3D |
ENSGALG00000012529 |
40887 |
0.961 |
- |
- |
- |
- |
0.961 |
- |
- |
- |
- |
- |
eukaryotic translation initiation factor 3 subunit D [Source:HGNC Symbol;Acc:HGNC:3278] |
19. |
RAB11A |
ENSGALG00000007615 |
9154 |
0.947 |
- |
- |
- |
- |
0.947 |
- |
- |
- |
- |
- |
RAB11A, member RAS oncogene family [Source:NCBI gene;Acc:415544] |
20. |
PAFAH1B1 |
ENSGALG00000005834 |
23532 |
0.939 |
- |
- |
- |
- |
- |
- |
0.939 |
- |
- |
- |
platelet activating factor acetylhydrolase 1b regulatory subunit 1 [Source:NCBI gene;Acc:374224] |
21. |
RBF |
RBF |
49711 |
0.939 |
- |
- |
- |
- |
- |
- |
0.939 |
- |
- |
- |
|
22. |
STK4 |
ENSGALG00000004098 |
11366 |
0.934 |
- |
- |
- |
- |
- |
- |
- |
0.934 |
- |
- |
serine/threonine kinase 4 [Source:NCBI gene;Acc:419187] |
23. |
TBC1D22B |
ENSGALG00000039130 |
3158 |
0.931 |
- |
- |
- |
- |
- |
- |
- |
0.931 |
- |
- |
TBC1 domain family member 22B [Source:HGNC Symbol;Acc:HGNC:21602] |
24. |
SEC31A |
ENSGALG00000040484 |
20190 |
0.927 |
- |
- |
- |
- |
- |
- |
0.927 |
- |
- |
- |
SEC31 homolog A, COPII coat complex component [Source:NCBI gene;Acc:422597] |
25. |
MRPL17 |
ENSGALG00000002605 |
46508 |
0.926 |
- |
- |
- |
- |
0.926 |
- |
- |
- |
- |
- |
mitochondrial ribosomal protein L17 [Source:HGNC Symbol;Acc:HGNC:14053] |
26. |
IST1 |
ENSGALG00000000811 |
10527 |
0.922 |
- |
- |
- |
- |
- |
- |
0.922 |
- |
- |
- |
IST1, ESCRT-III associated factor [Source:HGNC Symbol;Acc:HGNC:28977] |
27. |
RNF4 |
ENSGALG00000015668 |
15780 |
0.908 |
- |
- |
- |
- |
- |
- |
- |
0.908 |
- |
- |
ring finger protein 4 [Source:NCBI gene;Acc:422886] |
28. |
ZRANB2 |
ENSGALG00000011340 |
18994 |
0.907 |
- |
- |
- |
- |
- |
- |
0.907 |
- |
- |
- |
zinc finger RANBP2-type containing 2 [Source:NCBI gene;Acc:424717] |
29. |
PDCD11 |
ENSGALG00000008265 |
8665 |
0.902 |
- |
- |
- |
- |
- |
- |
0.902 |
- |
- |
- |
programmed cell death 11, transcript variant X2 |
30. |
WDR36 |
ENSGALG00000000247 |
11277 |
0.901 |
- |
- |
- |
- |
- |
- |
0.901 |
- |
- |
- |
WD repeat domain 36 [Source:NCBI gene;Acc:415609] |
31. |
COX7A2 |
ENSGALG00000015906 |
62347 |
0.901 |
- |
- |
- |
- |
- |
- |
0.901 |
- |
- |
- |
cytochrome c oxidase subunit 7A2 [Source:NCBI gene;Acc:772260] |
32. |
EPRS |
ENSGALG00000009598 |
26412 |
0.9 |
- |
- |
- |
- |
- |
- |
0.900 |
- |
- |
- |
glutamyl-prolyl-tRNA synthetase [Source:NCBI gene;Acc:421348] |
33. |
ODC1 |
ENSGALG00000016444 |
20119 |
0.891 |
- |
- |
- |
- |
- |
- |
0.891 |
- |
- |
- |
ornithine decarboxylase 1 [Source:NCBI gene;Acc:421937] |
34. |
NDUFB6 |
ENSGALG00000002033 |
45494 |
0.888 |
- |
- |
- |
- |
- |
- |
0.888 |
- |
- |
- |
NADH:ubiquinone oxidoreductase subunit B6 [Source:NCBI gene;Acc:416391] |
35. |
CHDZ |
CHDZ |
10381 |
0.886 |
- |
- |
- |
- |
- |
- |
0.886 |
- |
- |
- |
|
36. |
DAK |
DAK |
13208 |
0.88 |
- |
- |
- |
- |
- |
- |
0.880 |
- |
- |
- |
|
37. |
COPS4 |
ENSGALG00000011130 |
21515 |
0.876 |
- |
- |
- |
- |
0.876 |
- |
- |
- |
- |
- |
COP9 signalosome subunit 4 [Source:NCBI gene;Acc:422594] |
38. |
VMA21 |
ENSGALG00000009065 |
6432 |
0.876 |
- |
- |
- |
- |
- |
- |
- |
0.876 |
- |
- |
VMA21, vacuolar ATPase assembly factor [Source:NCBI gene;Acc:422385] |
39. |
RAB5A |
ENSGALG00000011272 |
17767 |
0.873 |
- |
- |
- |
- |
- |
- |
0.873 |
- |
- |
- |
RAB5A, member RAS oncogene family [Source:NCBI gene;Acc:420649] |
40. |
RWDD1 |
ENSGALG00000014953 |
9986 |
0.873 |
- |
- |
- |
- |
- |
- |
0.873 |
- |
- |
- |
RWD domain containing 1 [Source:NCBI gene;Acc:421741] |
41. |
BIRC5 |
ENSGALG00000008713 |
46856 |
0.873 |
- |
- |
- |
- |
- |
- |
0.873 |
- |
- |
- |
baculoviral IAP repeat containing 5 [Source:NCBI gene;Acc:374078] |
42. |
ENSGALG00000028938 |
ENSGALG00000028938 |
18616 |
0.871 |
- |
- |
- |
- |
- |
- |
0.871 |
- |
- |
- |
|
43. |
RBM25 |
ENSGALG00000009332 |
10842 |
0.871 |
- |
- |
- |
- |
- |
- |
0.871 |
- |
- |
- |
RNA binding motif protein 25 [Source:NCBI gene;Acc:423250] |
44. |
CHCHD4 |
ENSGALG00000006328 |
5860 |
0.869 |
- |
- |
- |
- |
- |
- |
0.869 |
- |
- |
- |
coiled-coil-helix-coiled-coil-helix domain containing 4 [Source:NCBI gene;Acc:416037] |
45. |
EXOC7 |
ENSGALG00000002050 |
9612 |
0.866 |
- |
- |
- |
- |
- |
- |
0.866 |
- |
- |
- |
exocyst complex component 7 [Source:NCBI gene;Acc:417361] |
46. |
HADHA |
ENSGALG00000016536 |
3791 |
0.865 |
- |
- |
- |
- |
- |
- |
- |
0.865 |
- |
- |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha [Source:NCBI gene;Acc:395929] |
47. |
ADD3 |
ENSGALG00000008542 |
13814 |
0.865 |
- |
- |
- |
- |
- |
- |
0.865 |
- |
- |
- |
adducin 3 (gamma) [Source:NCBI gene;Acc:373892] |
48. |
MCM2 |
ENSGALG00000006037 |
13458 |
0.865 |
- |
- |
- |
- |
- |
- |
- |
0.865 |
- |
- |
minichromosome maintenance complex component 2 [Source:NCBI gene;Acc:416027] |
49. |
DGCR2 |
ENSGALG00000005891 |
8405 |
0.864 |
- |
- |
- |
- |
- |
- |
- |
0.864 |
- |
- |
DiGeorge syndrome critical region gene 2 [Source:HGNC Symbol;Acc:HGNC:2845] |
50. |
SSU72 |
ENSGALG00000001489 |
7589 |
0.864 |
- |
- |
- |
- |
- |
- |
- |
0.864 |
- |
- |
SSU72 homolog, RNA polymerase II CTD phosphatase [Source:NCBI gene;Acc:419410] |
51. |
TSG101 |
ENSGALG00000006312 |
8289 |
0.864 |
- |
- |
- |
- |
- |
- |
- |
0.864 |
- |
- |
tumor susceptibility gene 101 [Source:NCBI gene;Acc:423082] |
52. |
WDR5 |
ENSGALG00000002659 |
13008 |
0.864 |
- |
- |
- |
- |
- |
- |
0.864 |
- |
- |
- |
WD repeat domain 5 [Source:NCBI gene;Acc:417144] |
53. |
NCAPD2 |
ENSGALG00000039448 |
8658 |
0.863 |
- |
- |
- |
- |
- |
- |
- |
0.863 |
- |
- |
non-SMC condensin I complex subunit D2 [Source:NCBI gene;Acc:418275] |
54. |
SLC4A1AP |
ENSGALG00000010047 |
3171 |
0.863 |
- |
- |
- |
- |
- |
- |
- |
0.863 |
- |
- |
solute carrier family 4 member 1 adaptor protein [Source:HGNC Symbol;Acc:HGNC:13813] |
55. |
MFAP3 |
ENSGALG00000004040 |
6951 |
0.863 |
- |
- |
- |
- |
- |
- |
0.863 |
- |
- |
- |
microfibrillar associated protein 3 [Source:NCBI gene;Acc:416261] |
56. |
IMPA1 |
ENSGALG00000034487 |
3691 |
0.863 |
- |
- |
- |
- |
- |
- |
- |
0.863 |
- |
- |
inositol monophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:6050] |
57. |
ING4 |
ENSGALG00000014457 |
5561 |
0.863 |
- |
- |
- |
- |
- |
- |
- |
0.863 |
- |
- |
inhibitor of growth family member 4 [Source:NCBI gene;Acc:418281] |
58. |
CYFIP1 |
ENSGALG00000016736 |
6701 |
0.863 |
- |
- |
- |
- |
- |
- |
- |
0.863 |
- |
- |
cytoplasmic FMR1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:13759] |
59. |
PSTK |
|
2511 |
0.862 |
- |
- |
- |
- |
- |
- |
- |
0.862 |
- |
- |
phosphoseryl-tRNA kinase, transcript variant X1 |
60. |
ENSGALG00000007096 |
ENSGALG00000007096 |
14595 |
0.862 |
- |
- |
- |
- |
- |
- |
0.862 |
- |
- |
- |
|
61. |
HAT1 |
ENSGALG00000009525 |
24864 |
0.862 |
- |
- |
- |
- |
- |
- |
0.862 |
- |
- |
- |
histone acetyltransferase 1 [Source:NCBI gene;Acc:374037] |
62. |
GLMN |
ENSGALG00000005959 |
2049 |
0.861 |
- |
- |
- |
- |
- |
- |
- |
0.861 |
- |
- |
glomulin, FKBP associated protein [Source:HGNC Symbol;Acc:HGNC:14373] |
63. |
URI1 |
ENSGALG00000004506 |
6024 |
0.861 |
- |
- |
- |
- |
- |
- |
- |
0.861 |
- |
- |
URI1, prefoldin like chaperone [Source:HGNC Symbol;Acc:HGNC:13236] |
64. |
RWDD3 |
ENSGALG00000038421 |
10909 |
0.86 |
- |
- |
- |
- |
- |
- |
- |
0.860 |
- |
- |
RWD domain containing 3 [Source:NCBI gene;Acc:424481] |
65. |
OGFOD3 |
ENSGALG00000001618 |
2438 |
0.86 |
- |
- |
- |
- |
- |
- |
- |
0.860 |
- |
- |
2-oxoglutarate and iron dependent oxygenase domain containing 3 [Source:HGNC Symbol;Acc:HGNC:26174] |
66. |
SIK1 |
ENSGALG00000041988 |
2179 |
0.859 |
- |
- |
- |
- |
- |
- |
- |
0.859 |
- |
- |
salt inducible kinase 1 [Source:NCBI gene;Acc:395417] |
67. |
NME3 |
ENSGALG00000027635 |
5974 |
0.859 |
- |
- |
- |
- |
- |
- |
- |
0.859 |
- |
- |
NME/NM23 nucleoside diphosphate kinase 3 [Source:NCBI gene;Acc:416399] |
68. |
EVC |
ENSGALG00000015037 |
1963 |
0.859 |
- |
- |
- |
- |
- |
- |
- |
0.859 |
- |
- |
EvC ciliary complex subunit 1 [Source:NCBI gene;Acc:422851] |
69. |
C1H11ORF67 |
C1H11ORF67 |
2089 |
0.858 |
- |
- |
- |
- |
- |
- |
- |
0.858 |
- |
- |
|
70. |
TIMM10 |
ENSGALG00000004845 |
31395 |
0.858 |
- |
- |
- |
- |
- |
- |
- |
0.858 |
- |
- |
translocase of inner mitochondrial membrane 10 [Source:NCBI gene;Acc:425202] |
71. |
TNFRSF1A |
ENSGALG00000039461 |
1569 |
0.857 |
- |
- |
- |
- |
- |
- |
- |
0.857 |
- |
- |
TNF receptor superfamily member 1A [Source:NCBI gene;Acc:418325] |
72. |
ARID3C |
ENSGALG00000005839 |
646 |
0.857 |
- |
- |
- |
- |
- |
- |
- |
0.857 |
- |
- |
AT-rich interaction domain 3C [Source:HGNC Symbol;Acc:HGNC:21209] |
73. |
SGTA |
ENSGALG00000014067 |
2248 |
0.857 |
- |
- |
- |
- |
- |
- |
- |
0.857 |
- |
- |
small glutamine rich tetratricopeptide repeat containing alpha [Source:NCBI gene;Acc:426396] |
74. |
RPL22L1 |
ENSGALG00000009312 |
59030 |
0.857 |
- |
- |
- |
- |
- |
- |
0.857 |
- |
- |
- |
ribosomal protein L22 like 1 [Source:NCBI gene;Acc:100858296] |
75. |
LANCL2 |
ENSGALG00000032570 |
815 |
0.857 |
- |
- |
- |
- |
- |
- |
- |
0.857 |
- |
- |
LanC like 2 [Source:HGNC Symbol;Acc:HGNC:6509] |
76. |
PGAP2 |
ENSGALG00000027762 |
2583 |
0.857 |
- |
- |
- |
- |
- |
- |
- |
0.857 |
- |
- |
post-GPI attachment to proteins 2 [Source:HGNC Symbol;Acc:HGNC:17893] |
77. |
TPMT |
ENSGALG00000012687 |
9537 |
0.856 |
- |
- |
- |
- |
- |
- |
- |
0.856 |
- |
- |
thiopurine S-methyltransferase [Source:HGNC Symbol;Acc:HGNC:12014] |
78. |
SPTBN5 |
|
395 |
0.856 |
- |
- |
- |
- |
- |
- |
- |
0.856 |
- |
- |
spectrin beta, non-erythrocytic 5 |
79. |
ARF6 |
ENSGALG00000026944 |
22014 |
0.855 |
- |
- |
- |
- |
- |
- |
- |
0.855 |
- |
- |
ADP ribosylation factor 6 [Source:NCBI gene;Acc:428927] |
80. |
C2orf47 |
C2orf47 |
17769 |
0.853 |
- |
- |
- |
- |
- |
- |
0.853 |
- |
- |
- |
|
81. |
ACAT2 |
ENSGALG00000011659 |
12825 |
0.853 |
- |
- |
- |
- |
- |
- |
0.853 |
- |
- |
- |
acetyl-CoA acetyltransferase 2 [Source:NCBI gene;Acc:421587] |
82. |
ASB3 |
ENSGALG00000008176 |
5422 |
0.851 |
- |
- |
- |
- |
- |
- |
0.851 |
- |
- |
- |
ankyrin repeat and SOCS box containing 3 [Source:NCBI gene;Acc:428545] |
83. |
NUDC |
ENSGALG00000000895 |
17844 |
0.851 |
- |
- |
- |
- |
- |
- |
0.851 |
- |
- |
- |
nuclear distribution C, dynein complex regulator [Source:NCBI gene;Acc:419578] |
84. |
ANGPTL2 |
ENSGALG00000000927 |
2580 |
0.851 |
- |
- |
- |
- |
- |
- |
- |
0.851 |
- |
- |
angiopoietin-like 2 [Source:NCBI gene;Acc:776031] |
85. |
LGMN |
ENSGALG00000010811 |
7401 |
0.85 |
- |
- |
- |
- |
- |
- |
0.850 |
- |
- |
- |
legumain [Source:HGNC Symbol;Acc:HGNC:9472] |
86. |
RILPL2 |
ENSGALG00000003321 |
5632 |
0.849 |
- |
- |
- |
- |
- |
- |
- |
0.849 |
- |
- |
Rab interacting lysosomal protein like 2 [Source:HGNC Symbol;Acc:HGNC:28787] |
87. |
FAM49A |
ENSGALG00000016463 |
6345 |
0.848 |
- |
- |
- |
- |
- |
- |
0.848 |
- |
- |
- |
family with sequence similarity 49 member A [Source:NCBI gene;Acc:421949] |
88. |
RNF130 |
ENSGALG00000005820 |
13797 |
0.848 |
- |
- |
- |
- |
- |
- |
0.848 |
- |
- |
- |
ring finger protein 130 [Source:HGNC Symbol;Acc:HGNC:18280] |
89. |
PAIP2 |
|
11856 |
0.847 |
- |
- |
- |
- |
- |
- |
0.847 |
- |
- |
- |
poly(A) binding protein interacting protein 2, transcript variant X1 |
90. |
PPP1R7 |
ENSGALG00000031766 |
22187 |
0.846 |
- |
- |
- |
- |
- |
- |
- |
0.846 |
- |
- |
protein phosphatase 1 regulatory subunit 7 [Source:NCBI gene;Acc:424844] |
91. |
TBCA |
ENSGALG00000004353 |
18510 |
0.846 |
- |
- |
- |
- |
- |
- |
0.846 |
- |
- |
- |
tubulin folding cofactor A [Source:NCBI gene;Acc:416367] |
92. |
AIMP1 |
ENSGALG00000010553 |
17994 |
0.844 |
- |
- |
- |
- |
- |
- |
0.844 |
- |
- |
- |
aminoacyl tRNA synthetase complex interacting multifunctional protein 1 [Source:HGNC Symbol;Acc:HGNC:10648] |
93. |
SPTAN1 |
ENSGALG00000004719 |
20251 |
0.843 |
- |
- |
- |
- |
- |
- |
0.843 |
- |
- |
- |
spectrin alpha, non-erythrocytic 1 [Source:NCBI gene;Acc:374234] |
94. |
PLOD1 |
ENSGALG00000004531 |
8256 |
0.843 |
- |
- |
- |
- |
- |
- |
0.843 |
- |
- |
- |
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 [Source:NCBI gene;Acc:419485] |
95. |
MRPS33 |
ENSGALG00000028879 |
17966 |
0.842 |
- |
- |
- |
- |
- |
- |
0.842 |
- |
- |
- |
mitochondrial ribosomal protein S33 [Source:NCBI gene;Acc:418119] |
96. |
PTDSS1 |
ENSGALG00000030185 |
5515 |
0.841 |
- |
- |
- |
- |
- |
- |
- |
0.841 |
- |
- |
phosphatidylserine synthase 1 [Source:NCBI gene;Acc:428374] |
97. |
SIGMAR1 |
ENSGALG00000028996 |
12267 |
0.837 |
- |
- |
- |
- |
- |
- |
0.837 |
- |
- |
- |
sigma non-opioid intracellular receptor 1 [Source:NCBI gene;Acc:100859748] |
98. |
SELT |
SELT |
25524 |
0.837 |
- |
- |
- |
- |
- |
- |
0.837 |
- |
- |
- |
|
99. |
ACO1 |
ENSGALG00000002162 |
6645 |
0.836 |
- |
- |
- |
- |
- |
- |
0.836 |
- |
- |
- |
aconitase 1, soluble [Source:NCBI gene;Acc:373916] |
100. |
BDH1_1 |
ENSGALG00000023601 |
6109 |
0.836 |
- |
- |
- |
- |
- |
- |
0.836 |
- |
- |
- |
3-hydroxybutyrate dehydrogenase, type 1 |